Moreover, statistical analysis indicates that the level of E2F1 was related to T stage (Fig. 7f), tumor differentiation (Fig. 7g), lymph node metastasis (Fig. 7i), and clinical stage (Fig. 7j), rather than age (Fig. 7e) and tumor primary locations (Fig. 7h) (Supplementary Table 2). Here, E2F1 is linked to neoplasm.