RT-qPCR showed significantly higher levels of CD163, CD204, CD206, IL-10, and CCL-22 mRNA, which indicates an M2-like immunophenotype, in macrophages selected from the gastric cancer tissues than in those from the adjacent non-cancerous tissues, whereas the expression level of the M1-subtype marker IL-23 was significantly lower in gastric cancer tissue-derived macrophages (Fig. 3b). Here, CCL22 is linked to gastric cancer.