HGF and acute respiratory distress syndrome: To study the effect of HGF in MSCs in the ALI mouse model, we used HGF-MSCs and shHGF-MSCs to treat LPS-induced ALI mice and evaluate lung pathological injury, DC phenotype, pulmonary edema, etc. This study provides an immunological explanation for the reduction of LPS-induced lung injury by MSCs via paracrine HGF.