SHISA3 and neoplasm: Herein, we found that 5 genes (Shisa3, PADI1, LRP2, ANGPTL4 and ALOX15B) were upregulated and 4 genes (CXCL9, ADAMDEC1, SCGB1A1/CC10, HLA-G) were downregulated in PR tumor tissues compared to SD tumor tissues (Fig. 1a).