Gene analysis in the lung tissues of αIFNAR1 mice showed a decreased in the expression of the M2 markers such as Arg1, Ym1, and Mrc1 (Fig. 5c-e), while high expression level of M1 markers such as Nos2 and Ifng were found compared with Isotype mice at 21 days post-infection (Fig. 5f-h) but no difference was observed at 84 days post infection. Here, ARG1 is linked to infection.