EPHX2 and major depressive disorder: Likewise, GDM women with the AA genotype in specific SNP of EPHX2 (G > A in rs17466684) is at 7.7 times odds more likely of getting stress symptoms compared to those who carry G allele in the SNP adjusted for ethnicity, religion, marital status, treatment regimens, past obstetric history of GDM, underlying with allergy and asthma and a family history of depression and anxiety.