These custom SNPs provide excellent coverage of many previously suggested and functionally important candidate genes for depression, anxiety and stress, including NPY5R [42,52]; ANO2 [42]; EPHX2 [42,51]; TPH2 [35]; NRG1 [34]; LHPP [38,39,54]; FKBP5 [41,45]; SDK2 [42]; RORA [33,55]; OXTR [27,28]; BDNF [56,57]; HTR2C [43]; TEX51 [42]; and PLEKHG1 [42]. This evidence concerns the gene EPHX2 and major depressive disorder.