EPHX2 and major depressive disorder: GDM women with the AA genotype in specific SNP of EPHX2 (G > A in rs17466684) are 7.9 times more likely to suffer from depression symptoms compared to those who carry G allele in the SNP, when adjusted for ethnicity, religion, practice of home glucose monitoring, planned pregnancy, marital status, past obstetric history of abortion, underlying with allergy, a family history of depression and anxiety and GDM.