Moreover, researchers have demonstrated that the secretion of hsa-miR-92a-3p by liposarcoma cells promotes the proliferation, invasion and metastasis of liposarcoma cells through this interaction with the surrounding microenvironment by extracellular vesicles and through stimulation of the secretion of the pro-inflammatory cytokine interleukin 6 in the TLR7/8-dependent manner of tumour-related macrophages [59]. This evidence concerns the gene IL6 and liposarcoma.