PTK2 and melanoma: Integrin signalling leads to the activation of FAK through the auto-phosphorylation of the Tyr-397 [44], therefore, we analysed in treated and untreated (NT) melanoma cells, the expression and the activation of FAK signalling protein (Figure 8C and Figure 9C) and we showed in (Bu2Sn)2TPPS-treated cells that the expression and the activation of FAK are almost at the steady state level in both cell lines (Figure 8C and Figure 9C, left and right panels).