Further investigations may help to understand the negative prognostic impact of RIG‐I in Type‐II OC, as RIG‐I high‐expressing tumors upregulated various markers suggestive of an immune‐suppressive tumor microenvironment: the immune checkpoints PD‐L1 (CD274) and PD‐1 (CD279)34 and the Treg‐specific transcription factor FoxP335 are all linked to high RIG‐I expression. Here, CD274 is linked to neoplasm.