There were significant positive correlations (r > 0.2) between the expression of CD204 and hypoxia marker HIF1A; cancer-associated fibroblast marker FAP; tumor immunosuppressive cytokines IL10, TGFB1, and TGFBR1; and multiple immunosuppressive checkpoints PDCD1/CD274, CD80, 86/CTLA4, LAG3, TIGHT, CD96, HAVCR2, and CD200/CD200R in all subtypes. The gene discussed is CD80; the disease is cancer.