As IFN-β can promote autophagy flux (Ambjørn et al., 2013) and alleviate models of neurodegenerative disease (Ejlerskov et al., 2015), we hypothesized that the therapeutic effect of IFN-β may, at least in part, be due to induction of miR-1. The gene discussed is IFNB1; the disease is neurodegenerative disease.