RET and non-small cell lung carcinoma: RET also plays a role in the development of the kidneys and the enteric nervous system.86, 87 When gene rearrangements involve RET, cells acquire oncogenic properties, as has been proven in thyroid papillary carcinoma.88 In about 1%–2% of NSCLC, RET‐involving gene rearrangements have been reported, according to the recent literature.