FOXP3 and immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome: Gambineri et al. performed an analysis of molecular, immunologic, and clinical features in a cohort of 173 patients presenting with IPEX-like symptoms, and based on FOXP3 gene sequencing, grouped them into IPEX kindreds (identifiable FOXP3 mutation) and IPEX-like kindreds (without FOXP3 mutation).