ESR1 and neoplasm: As shown in Table 1, FAM53A levels were negatively correlated with wild-type p53 (P < 0.001; Figures 1C,D), but had no significant correlation with age (P = 0.781); tumor size (P = 0.110); TNM stage (P = 0.056); lymph node metastasis (P = 0.996); or estrogen receptor, progesterone receptor, or human epidermal growth factor receptor 2 (HER-2) status (P = 0.069).