IL2-XE114-TNFmut bound to SKRC52 renal cell carcinoma cell lines more intensely than IL2-KSF-TNFmut (Figure 1H), which was specific to hen egg lysozyme and was chosen as a negative control of irrelevant specificity in the mouse (38) (Supplementary Figure 3). This evidence concerns the gene LYZ and hereditary clear cell renal cell carcinoma.