IQGAP1 and lip and oral cavity carcinoma: However, when we compared with sequencing data from the three non-OSCC cell lines, HeLa (cervical carcinoma), SF188, and KNS42 (pediatric gliomas), we found that only mutations in VAV2 and IQGAP1 genes seemed to be specific to oral cancers, as all three non-oral cancer lines displayed mutations in the other genes, but not in VAV2 and IQGAP1 (Fig. 2b, green boxes).