However, when we compared with sequencing data from the three non-OSCC cell lines, HeLa (cervical carcinoma), SF188, and KNS42 (pediatric gliomas), we found that only mutations in VAV2 and IQGAP1 genes seemed to be specific to oral cancers, as all three non-oral cancer lines displayed mutations in the other genes, but not in VAV2 and IQGAP1 (Fig. 2b, green boxes). The gene discussed is VAV2; the disease is lip and oral cavity carcinoma.