TPP1 and neoplasm: Our results (Figure 4C) showed that once we knocked down linc-GALMD1 in MSB1 cells, SRGN and TPP1 gene expression were significantly decreased, suggesting that linc-GALMD1 as a tumor suppressor may inhibit tumor growth via coordinating some genes including SRGN and TPP1. MD viral infection assays demonstrated that SRGN and TPP1 gene expression increased after the MDV infection in resistant line 63 (Figure 4C), which implied that SRGN and TPP1 play vital roles in resistance of the birds in response to MDV challenge.