ERBB2 and breast carcinoma: The Luminal A (LA) breast cancer is the most prevalent, constituting 50–70% of female breast cancer cases (DeSantis et al., 2017; Kwan et al., 2009), while the latter three subtypes are less common, constituting approximately 10–20% of all cases for Luminal B and Basal-Like, and 5–20% for HER2-Enriched.