Of the top 20 KEGG pathways IBD, cytokine-cytokine receptor interaction, TLR signaling pathway, pathways in cancer, CAMs, chemokine signaling pathway, Jak-STAT signaling pathway, and viral/bacterial infection related pathways [Measles, Tuberculosis, Influenza A, Herpes simplex infection, Hepatitis B, Leishmaniasis, Hepatitis C, Chagas disease (American trypanosomiasis), Toxoplasmosis, Malaria, Pertussis and Epstein-Barr virus infection] are the most biologically relevant. The gene discussed is SOAT1; the disease is Chagas disease.