STAMBP and post-traumatic stress disorder: Nevertheless, we found evidence that supports a role for POMC and one of its major downstream effectors, α-MSH, in the pathogenesis of antipsychotic-induced MetS, while there is so far only some evidence for a role of POMC in PTSD and in HPA axis regulation and no study demonstrating the involvement of POMC in PTSD-associated MetS.