In addition, we found that mRNA expression level of vimentin and synemin-β exhibited a significantly positive relationship with the mRNA expression level of GFAP in the control and the BPD patients but not in the MDD patients, which suggest that the connections between GFAP and vimentin or GFAP and synemin-β are stable in BPD but not in MDD. This evidence concerns the gene VIM and major depressive disorder.