ANGPT2 and cardiac arrhythmia: Interestingly, Fontan patients with history of arrhythmia had average Ang-2 levels of 9,692.5 ± 3,379.2 pg/mL compared to those with no arrhythmia history with levels of 6,374.7 ± 1,651.0 pg/mL which trended toward statistical significance (p = 0.07).