NDUFS8 and Behcet disease: Microarray studies within the PFC and HYP have also found significant reductions in expression of genes within the ETC, such as NDUFS7 and NDUFS8.18,19,30 However, a recent finding by Gandal et al.31 utilizing RNA-sequencing demonstrated no difference in the expression levels of NDUFS7 and NDUFS8 in cortical tissue of patients with BD,31 emphasizing the complexity and heterogeneity of BD.