In a study of hepatic stellate cells and liver fibrosis, the authors reported that the mechanism underlying liver fibrosis involved TNF‐α, which mediated NF‐κB activation in hepatic stellate cells and increased the ability of these cells to produce inflammatory cytokines.38 In the present study, we found that the levels of NF‐κB/p65 and IL‐6 were significantly increased in the cerulein‐induced CP mice model in vivo and in activated PSCs in vitro. Here, IL6 is linked to Hepatic fibrosis.