As shown in Fig. 2A, the systemic levels of CCL1 (GM of 7.64 pg/ml in bilateral vs. 5.53 pg/ml in unilateral disease), CCL3 (GM of 63.98 pg/ml in bilateral vs. 46.08 pg/ml in unilateral disease), CXCL1 (GM of 251.5 pg/ml vs. 186.6 pg/ml), CXCL2 (GM of 1488 pg/ml vs. 1047 pg/ml), CXCL10 (GM of 187.8 pg/ml vs. 121.2 pg/ml) and CXCL11 (GM of 334.3 pg/ml vs. 148.3 pg/ml) were significantly increased in PTB individuals with bilateral disease compared to unilateral disease. The gene discussed is CXCL11; the disease is glycogen storage disease VI.