TGFB1 and chronic obstructive pulmonary disease: In total, 96 miRNAs were significantly differentially expressed upon TGF-β stimulation in lung fibroblasts of controls and/or COPD patients, including the most abundantly expressed miRNAs miR-21-5p, miR-26a-5p, miR-221-3p and miR-222-3p (Supplementary Table 2).