VTA tracts demonstrated significantly decreased Thy1-YFP values in the ipsilateral hemisphere (as compared to the contralateral hemisphere) in stroke but not in control mice (Fig. 8c top row, mean asymmetry for stroke = 27.1%, control = 11.8%, p ≤ 0.0001 using two-sample t test, example tract profiles for stroke and control mice in Supplementary Fig. 12). The gene discussed is THY1; the disease is Stroke.