The top 20 GSEA pathways enriched in high-immunoscore were mainly immune related (all P < 0.002, Figure 6C), eight of which were the antitumor immunity pathways, including antigen process, B/T cell receptor signaling, Epstein-Barr virus infection, NK cell-mediated cytotoxicity, PD-L1 pathway, Th1, Th2 and Th7 cell differentiation (Figure 6D). This evidence concerns the gene CD274 and Epstein-Barr virus infection.