In accordance with our results in clinical samples, TCGA data also demonstrated much higher FOXM1 and Survivin mRNA levels in GBM and low-grade glioma (LGG) than in normal brain tissues (P < 0.05 or P < 0.01), and the correlation between them was positive and significant in both LGG and GBM (r = 0.70, P < 0.01) (Fig. 7b). The gene discussed is BIRC5; the disease is central nervous system cancer.