Pathogenic variants of the WNT10A gene (chromosome 2q35, OMIM 606268) are involved in the impairment of one or more ectodermal derivatives that cause HED, odonto-onycho-dermal dysplasia (OODD) (OMIM: # 257980; ORPHA: 2721), Schöpf-Schulz-Passarge syndrome (SSPS) (OMIM: # 224750; ORPHA: 50944) [9] and syndromic or non-syndromic NSTA (ORPHA: 99798) [10]. This evidence concerns the gene WNT10A and hypohidrotic ectodermal dysplasia.