By comparison, the proportion of CD3+ and CD3+CD4+cells were significantly lower in SCLC patients than controls (41.9 ± 14.5 vs. 55.6 ± 11.8, p < 0.001, Fig. 2a, b; 27.0 ± 9.43 vs. 33.5 ± 5.08, p = 0.0014, Fig. 2c, d). This evidence concerns the gene CD4 and small cell lung carcinoma.