This study established mouse model of lung cancer and demonstrated that commensal bacteria stimulated Myd88-dependent IL-1β and IL-23 production from myeloid cells, inducing proliferation and activation of Vγ6 + Vδ1+ γδT cells that produced IL-17 and other effector molecules which promote inflammation and tumor cell proliferation. This evidence concerns the gene MYD88 and lung carcinoma.