The patient had normal VHL gene sequencing via the 94 gene Illumina TruSight Cancer Kit on the Illumina MiSeq system, normal sanger sequencing of the VHL promoter region, normal VHL MLPA (salsa kit P016-C2) testing and normal bioinformatic analysis of other genes known to cause an inherited susceptibility to renal cancer using Illumina TruSight data. The gene discussed is VHL; the disease is renal carcinoma.