Among Hungarian patients with cardiovascular diseases, the frequency of carriers of genotype Tyr/Tyr of substitution Y54Cys (rs4148211) in the ABCG8 gene is lower among males younger than 50 with myocardial infarction, whereas the level of cholesterol is lower in Tyr/Tyr carriers than in the carriers of genotypes Tyr/Cys and Cys/Cys in a control sample [97]. Here, ABCG8 is linked to cardiovascular disorder.