LDLR (low-density lipoprotein receptor), APOB (apolipoprotein B), and PCSK9 (proprotein convertase subtilisin/kexin type 9) are the genes whose mutations determine the development of the autosomal dominant form of FH, and LDLRAP1 (low-density lipoprotein receptor adaptor protein 1) is a gene associated with the autosomal recessive form of the disease (Figure 1) [14]. This evidence concerns the gene LDLR and familial hyperaldosteronism.