SLC26A4 and Hyperkalemia: When Pendrin is genetically ablated in TgWnk4PHA2 mice, hyperkalaemia resolves and this could be due to enhanced BK activity in intercalated cells as the BK-β-4 subunit is present in intercalated cells with the BK-α subunit in addition to L-WNK1, which activates BK [62].