The expression and the role of eIF4B or eIF4H in gliomas have not yet been studied in details; however, the REMBRANDT data analysis shows a significant increase in EIF4B expression in oligodendrogliomas whereas no alteration was observed for neither of the two paralogues in GBM and astrocytomas compared to non-tumoral tissues. The gene discussed is EIF4B; the disease is central nervous system cancer.