Many studies have shown that p53 isoforms are abnormally expressed in breast cancer, ovarian cancer, lung cancer, colon carcinoma, glioblastoma, melanoma, head and neck tumors, renal cell carcinoma, acute myeloid leukemia, and hepatic cholangiocarcinoma [70,84,143,144,145,146,147,148,149,150,151]. Here, TP53 is linked to glioblastoma.