The premature ageing disorder Huntchinson–Gliford Progeria Syndrome (HGPS) is an extremely rare genetic disorder caused by a de novo point mutation in exon 11 of the LMNA gene, leading to the increased expression of a truncated splicing mutant of lamin A protein named progerin [107,108]. The gene discussed is LMNA; the disease is Hutchinson-Gilford progeria syndrome.