17, a region which included three genes: USP32 (ubiquitin specific peptidase 32), known to be overexpressed in breast cancer and colorectal metastatic disease [38], C17orf64 (an open reading frame) and APPBP2 (amyloid beta precursor protein binding protein 2), also highly expressed in breast cancer [39]. The gene discussed is APPBP2; the disease is breast cancer.