Previous studies have reported that Rbm14 may participate in NHEJ DNA repair by interacting with Ku80 in glioblastoma (GBM) and HeLa cells.21, 22 To further investigate the role of Rbm14 in DDR in ESCs and in early embryonic development, we performed Immunoprecipitation‐Mass Spectra (IP‐MS) with a GFP tagged Rbm14 (Gfp‐Rbm14) ESC cell line (Figure S4A) and identified 172 proteins that interacted with RBM14 protein (Figure 5A). The gene discussed is XRCC5; the disease is glioblastoma.