Kainic acid, an agonist of kainite‐class ionotropic glutamate receptors, has been widely used to induce status epilepticus in rodents to model spontaneous recurrent seizures in mTLE.16, 17 To reproduce the pathological changes of mTLE in mice, we performed intrahippocampal KA injections (20 mmol/L, 50 μL).16 and sacrificed the mice 1, 3, and 7 days postinjection to perform immunostaining for the neuronal marker NeuN and the microglial marker Iba1. Here, AIF1 is linked to status epilepticus.