conducted a parent‐of‐origin analysis investigating the effect of a child's FLG genotype and maternal and paternal FLG genotypes on the child's AD risk (n = 1209 families).29 Although interactions were not the focus of this study, results were stratified by maternal IgE sensitization status, allowing us to compare the effect of the child's FLG genotype in those whose mothers were or were not IgE sensitized. Here, IGHE is linked to Alzheimer disease.