AFM and metabolic syndrome: High afamin concentrations in human plasma are associated with all major parameters for metabolic syndrome, such as high blood glucose, as well as dyslipemia, obesity and high blood pressure, and also pre-eclampsia and ovarian cancer (Dieplinger et al., 2009 ▸; Kronenberg et al., 2014 ▸; Tramontana et al., 2018 ▸).