NEUROD1 and hydrops fetalis: After crossing a transgenic reporter of NF-κB activity Tg(NFkB:EGFP) (Kanther et al., 2011) with Tg(neurod1:RFP), we found that HF feeding significantly increased the number of NF-κB+ EECs (Figure 7K and P), but that this effect could be significantly reduced by treatment with orlistat or the ER stress inhibitor TUDCA (Figure 7L,M and P).