Furthermore, with the development of tumor molecular biology, a number of immunohistochemical and genomic markers related to the prognosis have emerged, like chromosome 1q status, YAP1 fusion, RELA fusion and so on.1, 2, 28 Due to the limitation of SEER database without genomic data, we failed to incorporate additional variables to improve our models. The gene discussed is RELA; the disease is neoplasm.