G6PD and thalassemia: It is reported that the G6PD enzyme activity in patients with G6PD deficiency compound thalassemia may be higher than that of G6PD deficiency patients, due to an increase in the number of newborn erythrocytes and increase in the activity of G6PD in the chronic hemolysis of the G6PD deficiency compound thalassemia patients.38, 39, 40 The patients with G6PD deficiency compound thalassemia may have normal G6PD activity, so such patients may be missed in the screening of G6PD activity.