Shenzhen assumed 4.34% of α‐thalassemia, in which the primary genotype was ‐‐SEA deletion (74.85% of mutations), 1.99% of β‐thalassemia in which CD41‐42(‐TCTT) and IVS‐II‐654(C → T) played a dominant role with frequencies 41.25% and 27.50%, respectively.30 Shaoguan manifested the prevalence was 10.44% of α‐thalassemia, in which ‐‐SEA deletion was 3.44%, 3.97% of β‐thalassemia with chief genotype of CD41‐42(‐TCTT).31 The genotypes and allele frequencies of Meizhou show some differences from Guangdong. Here, ITGA2B is linked to alpha thalassemia spectrum.