Several studies have been executed in different populations to decipher the role of VDR polymorphisms in T2D23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39and CAD.40, 41, 42, 43, 44, 45 To the best of our knowledge, studies on the importance of vitamin D or VDR polymorphisms in T2D patients with CAD are lacking. The gene discussed is VDR; the disease is type 2 diabetes mellitus.