It is important that combined genotype and serum vitamin D levels for FokI (Ff/deficient) and TaqI polymorphism (Tt/ insufficient, TT/deficient and Tt/deficient) were significantly more prevalent higher in T2D patients with CAD phenotype compared to those without CAD, indicating an important role of combined vitamin D and VDR variants with development of CAD in patients with T2D. Here, VDR is linked to type 2 diabetes mellitus.