First, we examined IL‐8, CXCR1 and CXCR2 expression in samples of ovarian serous cancer tissue and found the IL‐8, CXCR1 and CXCR2 were highly expressed in high‐grade ovarian serous cancer tissues than in low‐grade ovarian serous cancer tissues. The gene discussed is CXCL8; the disease is ovarian serous adenocarcinoma.