Thus, from our point of view, IL‐8 up‐regulated the Wnt signalling ligand Wnt5a expression, and subsequently activated a β‐catenin–dependent activation of Wnt pathway, which increased the expression of Wnt pathway cascade protein Met and c‐Jun, to finally induce a EMT process to promote the migration of ovarian cancer cells. The gene discussed is JUN; the disease is ovarian carcinoma.