TGFB1 and chronic obstructive pulmonary disease: Activation of TGF‐β by αvβ8‐expressing fibroblasts has been shown to drive DC chemotaxis in response to exogenous stimuli associated with COPD.75, 76 Recently, the potential efficacy of an integrin αvβ8‐targeted therapy for pulmonary fibrosis has been demonstrated in transgenic mice expressing human αvβ8.