For instance, integrin αvβ8‐mediated TGF‐β activation by DCs inhibits the differentiation of Th2 cells during infection with the intestinal parasite Trichuris muris, with mice lacking this pathway showing exacerbated Th2 cell numbers and protection from chronic infection.33 However, the ability of DC‐mediated TGF‐β activation to control responses to intestinal parasites is dependent on the pathogen, as recent data have shown that deletion of αvβ8 on DCs results in delayed expulsion of Trichinella spiralis. Here, TGFB1 is linked to infection.