NKTR is also increased in expression in our previous blood biomarker studies of suicide, in both males [8, 21], and females [22], as well as increased in expression in postmortem brain studies in depression [23] and in schizophrenia [24], possibly underlying the effect of stress on those disorders and, based on our new data, on decreasing memory retention and promoting AD. The gene discussed is NKTR; the disease is Alzheimer disease.