Johnson DC et al. reported that Val-boroPro, a non-selective inhibitor of the post-proline cleaving serine proteases, as well as the specific DPP8/9 inbibitors 1G244 and L-allo-Ile-isoindoline induced cell death in many AML cell lines and primary AML samples37. Here, DPP8 is linked to acute myeloid leukemia.